Spaceflight modulates gene expression in the whole blood of astronauts
نویسندگان
چکیده
منابع مشابه
Applicability of the actigraphy for astronauts in spaceflight
Pandi-Perumal and Gonfalone presented perspective on sleep in space by overviewing the past medical reports [3]. The authors made special emphasis on “normal sleep” in space, where no gravity exists. According to their review, sleep in space was mainly monitored by subjective sleep diaries and actigraphy (wrist-worn accelerometer). As sleep cycle was developed in response to the 24 h rotation o...
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The reactivation of cytomegalovirus (CMV) in 71 astronauts was investigated, using polymerase chain reaction. A significantly greater (P<.0001) shedding frequency was found in urine samples from astronauts before spaceflight (10.6%) than in urine from the healthy control subject group (1.2%). Two of 4 astronauts studied during spaceflight shed CMV in urine. A significant increase (P<.0001) in C...
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BACKGROUND Spaceflight causes changes in the cardiovascular control system. The aim of this study was to evaluate postflight recovery of linear and nonlinear neural markers of heart rate modulation, with a special focus on day-night variations. MATERIAL/METHODS Twenty-four-hour Holter ECG recordings were obtained in 8 astronauts participating in space missions aboard the International Space S...
متن کاملSubnormal norepinephrine release relates to presyncope in astronauts after spaceflight.
Postflight orthostatic intolerance is experienced by virtually all astronauts but differs greatly in degree of severity. We studied cardiovascular responses to upright posture in 40 astronauts before and after spaceflights lasting up to 16 days. We separated individuals according to their ability to remain standing without assistance for 10 min on landing day. Astronauts who could not remain st...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
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ژورنال
عنوان ژورنال: npj Microgravity
سال: 2016
ISSN: 2373-8065
DOI: 10.1038/npjmgrav.2016.39